Cholera is an acute diarrhoeal disease, which is caused by Vibrio cholerae. It's cases are characterized by Sudden onset as profusely, effortless, watery diarrhoea followed by vomiting/rapid dehydration muscular cramps and urine suppression.
It can cause epidemic, endemic and pandemic.Cholera epidemic in the community is Self limiting.
Causetive agents
Vibrio cholerae O group 1
How does it spreads?
The vibrio cholerae, cholera's bacteria is transmitted from one person to another through water contamination.How does it spreads?
Clinical features
90% of cases are mild & clinically diagnosed from other acute diarrhoea.
Cholera cases shows 3 stages.
1. stage of evacuation
• sudden unset
• profuse,painless watery diarrhoea
followed by vomiting
• 40 stools per day
• stool-Rice watery
2. stage of collapse
• Dehydration
• signs are sunken eye, hollow cheeks,
scaphoid abdomen,subnormal temp,
loss of skin elasticity,altered resp and
BP
• Decrease urine output
3. stage of recovery
If death doesn't occur the patient begin
to show sign of improvement
Diagnosis
• Collection of stool for lab examination
- Rubber catheter (Best method)
- Rectal swab
• Rapid cholera dipstick test
Treatments
The aim of treatment in cholera is to redydrate the patient.Drug therapy is much less important than rehydration
• Fluid replacement by orally or IV is the
first important steps
• Antibiotics:
Doxycycline is choice for adults
Cotrim is choice for Child
Furazolidone is choice for pregnant
• If diarrhoea persists after 48 hours of
treatment resistance to antibiotic
should be suspected.
Prevention
Hand Washing
• Proper hand washing with soap
• Proper cooking food and proper food
handling
• Proper access of safe and clean water
supply
• Environment sanitation
• Maintenance of personal hygiene
• Health education on Cholera
• Vaccination
# Better to know :
∆ V.cholerae is gram negative rod shaped
∆ Water is most important vehicle of
cholera transmission.
∆ CFR is 30-40%
∆ Isotonic fluid is given in cholera.
∆ Washerman's hand & feet are the
features of cholera.
∆ 90-95% acute case are treated with ORS
∆ ORS is essential treatment of cholera
∆ Cholera is notifiable disease Locally,
nationally & Internationally
∆ Vaccine: Dukoral(WC-rBS) & Sanchol
& mORCVAx are available
# To know more about cholera
in Hindi watch this video:
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